Tag: Cancer
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How to Analyze RNAseq Data for Absolute Beginners Part 16: A Comprehensive Tutorial on Identifying Fusion Genes
Understanding Fusion Genes: Key Concepts for Cancer Research What Are Fusion Genes and Why Do They Matter? Fusion genes represent a fascinating phenomenon in cancer biology where two previously separate genes join together, often creating proteins with altered or entirely new functions. These genetic mergers typically arise through chromosomal rearrangements like translocations, deletions, or inversions.
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Alternative Splicing Analysis ATAC-seq BAM cancer genomics ChIP-seq chromatin accessibility CNV DESeq2 Differential Expression edgeR FASTQ GATK Mutect2 gene expression heatmap HOMER HPC Isoform limma MACS2 MAF miRNA miRNA-seq MSigDB Normalization peak calling RNA-seq somatic mutations Transcript VCF whole genome sequencing